What condition may arise if the electrode-tissue interface becomes obstructed?

Electrode polarization refers to the formation of an insulating layer at the electrode-tissue interface, which can occur when there is an obstruction or inadequate contact between the electrode and surrounding tissue. This polarization hampers the ability of the electrode to effectively transmit electrical signals, leading to diminished performance of the implanted device.

When the interface is obstructed, it can disrupt the electrochemical processes necessary for effective pacing or sensing, negatively impacting the overall functionality of the cardiac device. This phenomenon is particularly relevant in situations where chronic inflammation or fibrotic tissue formation alters the interface dynamics.

In contrast, issues like lead migration, increased inflammation, and lead fracture relate to different mechanical or biological processes and do not directly stem from the obstructive effects on the electrode-tissue interface in the same way that electrode polarization does. Thus, understanding electrode polarization is crucial for maintaining the efficacy of cardiac rhythm management devices.